Supramolecular aspects of biomolecule interactions in metal–organic frameworks

This review focusses on the supramolecular interactions between metal–organic frameworks (MOFs) and included biomolecules. Examples demonstrating utility of crystallography, spectroscopic techniques, computational modelling for probing such are highlighted. Key papers illustrating importance intraframework to structure, flexibility, availability functional groups in bioMOFs also discussed. Finally, a range case studies focussing applications relating biosensing, drug delivery, contaminant removal enzyme immobilisation discussed as means highlighting how various characterisation techniques can work together provide an enhanced understanding chemistry involved their effects application.